Author

P. Simon

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 1 Microbiology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Research Focus:host-pathogen & immune response· 2 Research Focus:development & morphogenesis· 1 Research Focus:ecology & biodiversity· 1 Assay:metabolomics· 1 Assay:metagenomics· 1 Organism:mouse· 1 Organism:plant (other)· 1

Frequent Co-Authors

A. Fossoul· 1 shared B. L. Lee· 1 shared C. E. Stivala· 1 shared D. Demon· 1 shared E. L.- W. Majumder· 1 shared E. Silva· 1 shared F. Van Hauwermeiren· 1 shared G. A. Cagle· 1 shared

Activity by Year

2019-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

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1 shared paperImmunology

A. Fossoul

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Root exudation and rhizosphere microbial recruitment are influenced by novel plant trait diversity in carrot genotypes

H. M. Anderson, G. A. Cagle, E. L.- W. Majumder, E. Silva, J. Dawson, P. Simon, Z. B. Freedman

This study examines how root exudates and rhizosphere microbial communities vary across carrot genotypes, revealing genotype-specific effects on microbial recruitment and soil metabolite composition.

bioRxiv · Mar 12, 2024 · PreprintMicrobiology

MCC950/CRID3 potently targets the NACHT domain of wildtype NLRP3 but not disease-associated mutants for inflammasome inhibition

L. Vande Walle, I. B. Stowe, P. Sacha, B. L. Lee, D. Demon, A. Fossoul, F. Van Hauwermeiren, P. H. V. Saavedra, P. Simon, V. Subrt, L. Kostka, C. E. Stivala, V. C. Pham, S. T. Staben, S. Yamazoe, , M. Lamkanfi

This study identifies the NACHT domain of wildtype NLRP3 as the target of MCC950/CRID3, showing it inhibits inflammasome activity but not CAPS-associated mutants.

bioRxiv · May 11, 2019Immunology