Molecular mechanism of translational stalling by inhibitory codon combinations and poly(A) tracts
P. Tesina, L. N. Lessen, R. Buschauer, J. Cheng, C. C.-C. Wu, O. Berninghausen, A. R. Buskirk, T. Becker, R. Beckmann, R. Green
This study identifies molecular mechanisms of translational stalling caused by inhibitory codon pairs and poly(A) tracts using in vitro biochemistry, ribosome profiling, and cryo-EM.
bioRxiv · Sep 4, 2019Biochemistry