Synthesis and Structure Elucidation of the Human tRNA Nucleoside Mannosyl-Queuosine
T. Carell, M. Hillmeier, M. Wagner, T. Ensfelder, E. Korytiakova, P. Thumbs, M. Mueller
The paper reports the correct structure of mannosyl-queuosine (manQ) through total synthesis and LC-MS-co-injection, revealing a novel -allyl connectivity and differing glycosylase preferences.
bioRxiv · Jun 24, 2021Biochemistry