Genome-wide analysis of focal DNA hypermethylation in IDH-mutant AML samples
E. R. Wilson, N. Helton, S. E. Heath, R. S. Fulton, C. Miller, J. E. Payton, J. S. Welch, M. Walter, P. Westervelt, J. F. DiPersio, D. C. Link, T. J. Ley, D. H. Spencer
This study identifies focal DNA hypermethylation in IDH-mutant AML samples and links it to TET2 and DNMT3A activity, with implications for AML pathogenesis.
bioRxiv · Mar 3, 2021 · PreprintCancer Biology