Author

P. Zegerman

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 3

Signature Assays, Organisms & Methods

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Research Focus:chromatin & epigenetic regulation· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:development & morphogenesis· 2 Approach:experimental assay· 2 Organism:yeast· 2 Organism:C. elegans· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

A. Klucnika· 1 shared B. Schöpf· 1 shared D. Alexander· 1 shared F. L. V. Jenkinson· 1 shared G. Can· 1 shared I. Phanada· 1 shared K. W. Tan· 1 shared M. C. Johnson· 1 shared

Activity by Year

2020-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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1 shared paperCell Biology

A. Klucnika

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Author profile →

3 papers

Recent·Most cited

Dephosphorylation of the pre-initiation complex during S-phase is critical for origin firing

F. L. V. Jenkinson, K. W. Tan, B. Schöpf, M. M. Santos, I. Phanada, P. Zegerman

This study shows that dephosphorylation of Sld2 and Sld3 by PP2A and PP4 phosphatases is essential for replication origin firing in yeast.

bioRxiv · Nov 2, 2021 · PreprintCell Biology

Checkpoint inhibition of origin firing prevents inappropriate replication outside of S-phase

M. C. Johnson, G. Can, M. Santos, D. Alexander, P. Zegerman

This study shows that the S-phase checkpoint, via Rad53 kinase, inhibits replication initiation factors beyond S-phase, preventing re-replication and inappropriate gene amplification in G2/M and G1 phases.

bioRxiv · Sep 30, 2020Cell Biology

Identification of the critical replication targets of CDK reveals direct regulation of replication initiation factors by the embryo polarity machinery in C. elegans

V. Gaggioli, M. R. Kieninger, A. Klucnika, R. Butler, P. Zegerman

This study identifies CDK's role in regulating replication initiation factors in C. elegans embryos, showing direct coordination between embryo polarity and DNA replication.

bioRxiv · Jun 24, 2020Cell Biology