Author

M. M. Santos

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Pharmacology & Toxicology· 3 Cell Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:bulk RNA-seq· 2 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:differential expression· 2 Organism:zebrafish· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1

Frequent Co-Authors

S. Barros· 3 shared T. Neuparth· 3 shared J. B. Quintana· 2 shared N. Alves· 2 shared R. Montes· 2 shared R. Rodil· 2 shared A. Andre· 1 shared A. Capitao· 1 shared

Activity by Year

2018-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 32 mutual co-author links

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3 shared papersPharmacology & Toxicology

S. Barros

Mutual co-authors in cluster

Author profile →

4 papers

Recent·Most cited

Pharmacology & ToxicologybioRxivPreprintApr 5, 2022

Metformin disrupts Danio rerio metabolism at environmentally relevant concentrations: A generational study

S. Barros, M. Ribeiro, A. M. Coimbra…·T. Neuparth

This study shows that metformin disrupts zebrafish metabolism at environmentally relevant concentrations, affecting lipid homeostasis and mitochondrial function across generations.

DOI 10.1101/2022.04.05.487223

zebrafishbulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivPreprintNov 2, 2021

Dephosphorylation of the pre-initiation complex during S-phase is critical for origin firing

F. L. V. Jenkinson, K. W. Tan, B. Schöpf…·P. Zegerman

This study shows that dephosphorylation of Sld2 and Sld3 by PP2A and PP4 phosphatases is essential for replication origin firing in yeast.

DOI 10.1101/2021.11.02.466916

yeastexperimental assay

𝕏 PostBluesky

Pharmacology & ToxicologybioRxivApr 23, 2020

The anti-lipidemic drug simvastatin modulates Epigenetic Biomarkers in the Amphipod Gammarus locusta

N. Alves, T. Neuparth, S. Barros, M. M. Santos

This study examines how simvastatin affects epigenetic markers in the amphipod Gammarus locusta, showing downregulation of DNA methyltransferase1 and global DNA hypomethylation at specific concentrations.

DOI 10.1016/j.ecoenv.2020.111849

non-human primateDNA methylation

𝕏 PostBluesky

Pharmacology & ToxicologyAquatic ToxicologyPeer-reviewedAug 1, 2018

Chronic environmentally relevant levels of Simvastatin induces non-monotonic responses in Zebrafish (Danio rerio)

S. Barros, R. Montes, J. B. Quintana…·T. Neuparth

This study investigates the chronic effects of simvastatin on zebrafish at environmentally relevant concentrations, finding non-monotonic dose responses in embryonic development, biochemistry, and gene expression.

DOI 10.1016/j.aquatox.2018.05.014

zebrafishbulk RNA-seq

𝕏 PostBluesky