Author

P.K. Newton

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:drug response / drug discovery· 1 Approach:mechanistic / dynamical model· 1 Approach:statistical model· 1

Frequent Co-Authors

Y. Ma· 2 shared

Activity by Year

2018-2018 · peak 2/yr

2 papers

Recent·Most cited

Cancer BiologybioRxivPreprintMay 17, 2018

On the design of treatment schedules that avoid chemotherapeutic resistance

Y. Ma, P.K. Newton

This paper designs treatment schedules using evolutionary game theory to avoid chemotherapeutic resistance by maintaining population balance through periodic dose switching.

DOI 10.1101/325381

mechanistic / dynamical modeldrug response / drug discovery

𝕏 PostBluesky

Cancer BiologybioRxivPreprintApr 12, 2018

Nonlinear dynamics of chemotherapeutic resistance

Y. Ma, P.K. Newton

This study uses a replicator dynamical system to show that pre-existing resistant cells lead to chemotherapeutic resistance through competitive release.

DOI 10.1101/300582

statistical model

𝕏 PostBluesky