Synthetic BiologyNature CommunicationsPeer-reviewed
Development of a p62 biodegrader for autophagy targeted degradation
Zacharias Thiel, David Marcellin, Carole Manneville…·Beat Nyfeler
The paper develops a p62-based biodegrader that selectively degrades mitochondria via autophagy but not cytosolic proteins due to its effect on p62 self-oligomerization.
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