Cancer BiologybioRxivPreprint
Analysis of patient derived xenograft studies in Oncology drug development: impact on design and interpretation of future studies
Jake Dickinson, Marcel de Matas, Paul A Dickinson, Hitesh Mistry
This paper compares model-based analysis and un-paired t-test for PDX xenograft studies, finding model-based methods more powerful and capable of detecting smaller treatment effects.
DOI 10.1101/579136