Molecular BiologyCell ReportsPeer-reviewed
mTORC1 activity oscillates throughout the cell cycle promoting mitotic entry and differentially influencing autophagy induction
Jay N. Joshi, Ariel D. Lerner, Frank Scallo…·Alexander J. Valvezan
This study shows mTORC1 activity oscillates during the cell cycle, peaks in S and G2, and is lowest in mitosis and G1, with distinct regulatory mechanisms and functional consequences.
25 citations