Cancer BiologybioRxivPreprint
Enhanced antitumour activity of combined PD-1 blockade and HER2-targeted therapy is associated with reduced epithelial-mesenchymal transition and extracellular matrix-remodelling signatures in gastric cancer
Peter Kok-Ting Wan, Shuang Peng, Xiangrui Zhang, Jian Wang
This study shows that combining PD-1 blockade and HER2-targeted therapy in gastric cancer reduces EMT and extracellular matrix remodelling while enhancing cytotoxic immune signatures.
DOI 10.64898/2026.11.08.765160