Author

Prema C. Iyer

University of Pittsburgh

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

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Pharmacology & Toxicology· 1

Signature Assays, Organisms & Methods

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Organism:human· 1 Approach:mechanistic / dynamical model· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

Frequent Co-Authors

Ari M. SelzeriD· 1 shared Carlos Jaime CamachoiD· 1 shared Gabriella GerlachiD· 1 shared Giancarlo Gonzalez-Areizaga· 1 shared John R. EngeniD· 1 shared Rieko IshimaiD· 1 shared Stephanie Y. Cui· 1 shared Thomas E. SmithgalliD· 1 shared

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2024-2024 · peak 1/yr

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9 top collaborators · 36 mutual co-author links

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1 shared paperPharmacology & Toxicology

Ari M. SelzerORCID

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1 paper

Recent·Most cited

Pharmacology & ToxicologyJournal of Biological ChemistryPeer-reviewedDec 13, 2024

An SH3-binding allosteric modulator stabilizes the global conformation of the AML-associated Src-family kinase, Hck

Ari M. Selzer, Gabriella Gerlach, Giancarlo Gonzalez-Areizaga…·Thomas E. Smithgall

This study identifies PDA1 as an SH3-binding allosteric modulator that stabilizes Hck conformation, potentially enhancing combination therapy with ATP-site inhibitors.

3 citations

humanproteomics

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