Author

Prithi A Srinivasan

University of Chicago

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Assay:proteomics· 2 Approach:biophysical modeling· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:protein folding & dynamics· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

Alexander J. RuthenburgiD· 2 shared Amanda J. KeplingeriD· 2 shared Beatrix M. UeberheideiD· 1 shared Cristian SuareziD· 1 shared Juliana Ortiz-PachecoiD· 1 shared Sarah M. ChristenseniD· 1 shared Tyler C. CropleyiD· 1 shared

Activity by Year

2025-2026 · peak 1/yr

Co-Author Collaboration Network

7 top collaborators · 15 mutual co-author links

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2 shared papersMolecular Biology

Alexander J. RuthenburgORCID

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2 papers

Recent·Most cited

Molecular BiologybioRxivPreprintMay 14, 2026

Bound for the nucleus: defining the molecular principles of cargo selection by importin 9

Amanda J. Keplinger, Tyler C. Cropley, Juliana Ortiz-Pacheco…·Beatrix M. Ueberheide

This study identifies 79 cargos bound by IPO9, showing it recognizes proteins without cNLSs, and defines structural elements that mediate cargo selection and release.

DOI 10.64898/2026.05.12.724649

proteomicsexperimental assay

𝕏 PostBluesky

BiochemistryJournal of Biological ChemistryPeer-reviewedDec 31, 2025

A revised model of nuclear actin import: Importin 9 competes with cofilin, profilin, and RanGTP for actin binding

Amanda J. Keplinger, Prithi A Srinivasan, Sarah M. Christensen…·Alexander J. Ruthenburg

This paper challenges the established model of actin import by showing IPO9 directly binds monomeric actin and competes with cofilin and profilin for actin binding.

2 citations

proteomicsbiophysical modeling

𝕏 PostBluesky