Cancer BiologybioRxivPreprint
CRISPR-Mediated Targeting of BRAF Oncogenes in Pediatric Low-Grade Glioma
Christy A George, Margaret E. Brown, Priya Rana…·Ross C. Wilson
This study develops and validates CRISPR guide RNAs to target BRAF oncofusions and V600E mutations in pediatric low-grade glioma cells, achieving high indel frequencies and confirming junction excision.
DOI 10.64898/2026.08.12.744431