Molecular BiologybioRxivPreprint
Transcription-associated topoisomerase activities control DNA-breaks production by G-quadruplex ligands
Angélique Pipier, Madeleine Bossaert, Jean‐François Riou…·Dennis Gómez
The paper identifies TOP2A as a key effector of cytotoxicity from G4 ligands and shows its role in DNA break production during transcription.
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