Angélique Pipier

This study shows QN-302 damages DNA at G4 sites in cancer cells and its anticancer effect is enhanced by Olaparib, a DNA repair inhibitor.

This study investigates G-quadruplex (G4) formation in three lncRNAs dysregulated in colorectal cancer and shows their stable G4 structures using in silico and in vitro methods.

The paper introduces two clickable G4 ligands for visualizing and identifying G4s in human cells using click chemistry protocols.

The paper identifies TOP2A as a key effector of cytotoxicity from G4 ligands and shows its role in DNA break production during transcription.