Cancer BiologybioRxiv
Mitochondrial dsRNA from B-ALL cells stimulates mesenchymal stromal cells to become cancer associated fibroblasts
R. J. Burt, A. Dey, A. Akarca…·A. K. Fielding
This study shows that mitochondrial dsRNA from B-ALL cells triggers MSC to become CAFs, linking genetic subtypes to survival outcomes.
DOI 10.1182/bloodadvances.2023012077