Author

R. Baccouch

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 2 Approach:experimental assay· 2 Organism:human· 2 Assay:proteomics· 2 Research Focus:drug response / drug discovery· 1 Approach:genetic perturbation / CRISPR· 1

Frequent Co-Authors

I. Alves· 2 shared P. Trifilieff· 2 shared T. Durroux· 2 shared V. De Smedt-Peyrusse· 2 shared A. A. Mali· 1 shared A. Gorse· 1 shared A. Oummadi· 1 shared B. Medel Lacruz· 1 shared

Activity by Year

2022-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersCell Biology

I. Alves

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Membrane lipid poly-unsaturation selectively affects dopamine D2 receptor internalization

S. Sposini, R. Baccouch, M. Lescuyer, A. A. Mali, V. De Smedt-Peyrusse, J. Heuninck, A. Gorse, T. Durroux, P. Trifilieff, D. Perrais, I. Alves

This study shows that membrane poly-unsaturated fatty acids (PUFAs) impair dopamine D2 receptor (D2R) endocytosis without affecting other GPCRs or clathrin-mediated endocytosis.

bioRxiv · Dec 14, 2023 · PreprintCell Biology

Impact of membrane lipid polyunsaturation on dopamine D2 receptor ligand binding and signaling

M.-L. Jobin, V. De Smedt-Peyrusse, F. Ducrocq, A. Oummadi, R. Baccouch, M. Hauge Pedersen, B. Medel Lacruz, P. Van-Delft, L. Fouillen, S. Mongrand, J. Selent, T. Tolentino-Cortez, G. Barreda-Gomez, S. Gregoire, E. Masson, , P. Trifilieff

This study shows that n-3 PUFAs enhance D2R ligand binding and signaling, suggesting they act as allosteric modulators of the receptor.

bioRxiv · Jan 4, 2022Cell Biology