Ligands tune the local and global motions of neurotensin receptor 1 (NTS1): a DFT-guided solution NMR analysis
F. Bumbak, M. Pons, A. Inoue, J. C. Paniagua, F. Yan, H. Wu, S. A. ROBSON, R. Bathgate, D. J. Scott, P. R. Gooley, J. J. Ziarek
This study uses NMR and DFT to analyze sub-nanosecond motions of NTS1, showing ligands affect conformational entropy and dynamics.
bioRxiv · Aug 9, 2022Biophysics