R. Becker

N-cadherin mechanosensing in ovarian follicles controls oocyte maturation and ovulation

This study shows N-cadherin mechanosensing regulates ovarian follicle structure, oocyte maturation, and ovulation by modulating Hippo/YAP and β-catenin pathways.

Simulated tempering-enhanced umbrella sampling improves convergence of free energy calculations of drug membrane permeation

This study introduces STeUS, a method combining simulated tempering and umbrella sampling to improve convergence of free energy calculations for drug membrane permeation, showing significant acceleration for bulky molecules.

Plastid DNA sequences and oospore characters of some European species of Tolypella section Tolypella (Obtusifolia, Characeae) indicate a new cryptic Tolypella species from the Mediterranean island Sardinia

The paper uses plastid DNA sequences and oospore morphology to reclassify Tolypella species in Europe, identifying a new cryptic species from Sardinia.

Exploration and analysis of molecularly annotated, 3D models of breast cancer at single-cell resolution using virtual reality

The paper introduces Theia, a virtual reality platform for exploring 3D molecularly annotated cancer datasets, and provides breast cancer datasets for analysis.

Alternative splicing of pericentrin contributes to cell cycle control in cardiomyocytes

This study shows that alternative splicing of pericentrin (Pcnt) contributes to cell cycle arrest in postnatal cardiomyocytes by affecting centriole cohesion and DNA synthesis.

Generation and first characterization of TRDC-Knockout pigs lacking γδ T cells

This study generates TRDC-knockout pigs lacking γδ T cells and finds they have altered immune responses but no developmental abnormalities.

Expansion Sequencing: Spatially Precise In Situ Transcriptomics in Intact Biological Systems

ExSeq enables multiplexed RNA mapping at nanoscale resolution by expanding biological specimens for in situ sequencing.

Myogenin controls via AKAP6 non-centrosomal microtubule organizing center formation at the nuclear envelope

The paper identifies myogenin's role in inducing AKAP6 and nesprin-1 to form non-centrosomal MTOCs at the nuclear envelope in muscle cells.

Transient spectral events in resting state MEG predict individual time-frequency task responses

The paper predicts individual task responses from resting-state MEG transient spectral events across multiple tasks and subjects.