Author

A. Frenzel

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 3 Bioengineering· 1 Immunology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 5 Organism:human· 4 Research Focus:cell signaling & trafficking· 2 Assay:bulk RNA-seq· 1 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1 Research Focus:differential expression· 1 Research Focus:host-pathogen & immune response· 1

Frequent Co-Authors

E. Fischer-Friedrich· 3 shared K. Hosseini· 3 shared A. Breithaupt· 1 shared A. Gerstner· 1 shared A. Hermann· 1 shared A. Koch· 1 shared A. Lucas-Hahn· 1 shared B. Petersen· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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3 shared papersBiophysics

E. Fischer-Friedrich

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

EMT induces cell-cycle-dependent changes of Rho GTPases and downstream effectors

K. Hosseini, A. Frenzel, E. Fischer-Friedrich

The paper shows EMT in breast cancer cells causes cell-cycle-dependent changes in Rho GTPases and downstream effectors, proposing two new signalling pathways.

bioRxiv · Feb 2, 2023 · PreprintBiophysics

Skin epithelial cells change their mechanics and proliferation upon Snail-mediated EMT signalling

K. Hosseini, P. Trus, A. Frenzel, C. Werner, E. Fischer-Friedrich

This study shows that Snail-mediated EMT in skin epithelial cells alters cellular mechanics, mitotic rounding, and proliferation, with implications for skin tumor progression.

bioRxiv · Feb 1, 2022Biophysics

Generation and first characterization of TRDC-Knockout pigs lacking γδ T cells

B. Petersen, R. Kammerer, A. Frenzel, P. Hassel, T. H. Dau, R. Becker, A. Breithaupt, R. Ulrich, A. Lucas-Hahn, G. Meyers

This study generates TRDC-knockout pigs lacking γδ T cells and finds they have altered immune responses but no developmental abnormalities.

bioRxiv · Mar 27, 2021Immunology

EMT changes actin cortex rheology in a cell-cycle dependent manner

K. Hosseini, A. Frenzel, E. Fischer-Friedrich

This study examines how EMT affects actin cortex rheology in human epithelial cells, finding cell-cycle dependent softening in interphase and stiffening in mitosis.

bioRxiv · Dec 15, 2020Biophysics

A SARS-CoV-2 neutralizing antibody selected from COVID-19 patients by phage display is binding to the ACE2-RBD interface and is tolerant to most known recently emerging RBD mutations

F. Bertoglio, V. Fühner, M. Ruschig, P. A. Heine, L. Abasi, T. Klünemann, U. Rand, D. Meier, N. Langreder, S. Steinke, R. Ballmann, K.-T. Schneider, K. D. R. Roth, P. Kuhn, P. Riese, , M. Hust

The paper describes the selection of a SARS-CoV-2 neutralizing antibody from COVID-19 patients using phage display, showing it binds the ACE2-RBD interface and remains effective against emerging RBD mutations.

bioRxiv · Dec 3, 2020Bioengineering