Author

R. Benedetti

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cancer Biology· 1

Signature Assays, Organisms & Methods

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Organism:human· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:chromatin & epigenetic regulation· 1 Approach:deep learning· 1 Assay:DNA methylation· 1 Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1 Approach:statistical model· 1

Frequent Co-Authors

L. Altucci· 2 shared A. Chambery· 1 shared A. D'Aniello· 1 shared A. J. Cesare· 1 shared A. P. Sobinoff· 1 shared C. Altucci· 1 shared F. Bajardi· 1 shared G. Franci· 1 shared

Activity by Year

2021-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 27 mutual co-author links

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2 shared papersCancer Biology

L. Altucci

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Irreversible inhibition of TRF2TRFH recruiting functions: a strategy to induce telomeric replication stress in cancer cells.

A. P. Sobinoff, S. Di Maro, R. R. J. Low, R. Benedetti, S. Tomassi, A. D'Aniello, R. Russo, I. Baglivo, U. Chianese, P. V. Pedone, A. Chambery, A. J. Cesare, L. Altucci, H. A. Pickett, S. Cosconati

This paper identifies APOD53, a covalent cyclic peptide that irreversibly inhibits TRF2TRFH domain function, inducing telomeric replication stress and impairing cancer cell growth.

bioRxiv · Feb 1, 2023 · PreprintCancer Biology

DNA Mutations via Chern-Simons Current

F. Bajardi, L. Altucci, R. Benedetti, S. Capozziello, M. R. Del Sorbo, G. Franci, C. Altucci

The paper uses Chern-Simons theory to analyze DNA curvature and mutation positions in KRAS and COVID-19 sequences, finding mutations correlate with high curvature gradients and smoother post-mutation curvature.

bioRxiv · Jun 22, 2021Biophysics