Author

R. Brais

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

Click to filter author papers

Cancer Biology· 2

Signature Assays, Organisms & Methods

Click to filter · or open tag

Approach:experimental assay· 2 Organism:mouse· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell signaling & trafficking· 1 Research Focus:development & morphogenesis· 1 Research Focus:host-pathogen & immune response· 1 Research Focus:metabolism & bioenergetics· 1 Assay:proteomics· 1

Frequent Co-Authors

A. Dannhorn· 1 shared A. G. Schuller· 1 shared A. R. Young· 1 shared B. M. Weigand· 1 shared B. P. Kaistha· 1 shared C. N. Young· 1 shared D. I. Jodrell· 1 shared D. Jurk· 1 shared

Activity by Year

2019-2022 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 21 mutual co-author links

Click any collaborator node to inspect or filter shared papers

Focal author (center)Selected co-authorORCID co-authorUnlinked name

Curved chords = mutual co-authorship

1 shared paperCancer Biology

A. Dannhorn

Mutual co-authors in cluster

Author profile →

2 papers

Recent·Most cited

Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma

V. Graziano, A. Dannhorn, H. Hulme, K. Williamson, H. Buckley, S. A. Karim, S. Y. Lee, B. P. Kaistha, S. Islam, J. E. D. Thaventhiran, F. M. Richards, R. Goodwin, R. Brais, J. P. Morton, S. J. Dovedi, , D. I. Jodrell

This study shows that extracellular adenosine promotes an immunosuppressive microenvironment in PDAC by enhancing myeloid cell infiltration and resistance to immunotherapy, and that blocking adenosine pathway components improves therapeutic outcomes.

bioRxiv · May 24, 2022Cancer Biology

Temporal inhibition of autophagy reveals segmental reversal of aging with increased cancer risk

L. Cassidy, A. R. Young, C. N. Young, E. J. Soilleux, E. Fielder, B. M. Weigand, R. Brais, K. A. Wiggins, M. C. Clarke, D. Jurk, J. F. Passos, M. Narita

This study shows that inhibiting autophagy in mammals accelerates aging and increases cancer risk, while restoring autophagy extends lifespan but does not fully prevent cancer.

bioRxiv · Jan 23, 2019 · PreprintCancer Biology