Author

K. Williamson

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 2 Cancer Biology· 1 Evolutionary Biology· 1 Immunology· 1 Plant Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:mouse· 3 Research Focus:cell type annotation· 2 Research Focus:host-pathogen & immune response· 2 Assay:proteomics· 2 Approach:statistical model· 2 Research Focus:chromatin & epigenetic regulation· 1 Research Focus:differential expression· 1

Frequent Co-Authors

D. I. Jodrell· 2 shared J. E. D. Thaventhiran· 2 shared A. Carter· 1 shared A. Dannhorn· 1 shared A. G. B. Simpson· 1 shared A. G. Schuller· 1 shared A. J. Roger· 1 shared A. McDowell· 1 shared

Activity by Year

2020-2023 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 12 mutual co-author links

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2 shared papersImmunology

D. I. Jodrell

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Author profile →

6 papers

Recent·Most cited

Meteora sporadica, a protist with incredible cell architecture, is related to Hemimastigophora.

Y. Eglit, T. Shiratori, J. Jerlström-Hultqvist, K. Williamson, A. J. Roger, K.-I. Ishida, A. G. B. Simpson

The paper describes Meteora sporadica, a protist with unique morphology, and shows its close phylogenetic relationship to Hemimastigophora through genomic analysis.

bioRxiv · Aug 13, 2023Evolutionary Biology

Fate-mapping lymphocyte clones and their progenies from induced antigen-signals identifies temporospatial behaviours of T cells mediating tolerance

M. Takahashi, T. So, K. Williamson, Z. Hosseini, K. Kania, M. Ruhle, T. Mann, M. J. Schujis, P. Coupland, D. Naisbitt, T. Y. F. Halim, P. A. Lyons, P. Lio, K. Okkenhaug, D. J. Adams, , J. E. D. Thaventhiran

This study introduces a novel fate-mapping mouse to track lymphocyte clones and their progenies in response to antigen signals, revealing distinct T cell behaviors in tumor immunity.

bioRxiv · Mar 16, 2023Immunology

Defining the spatial distribution of extracellular adenosine revealed a myeloid-dependent immunosuppressive microenvironment in pancreatic ductal adenocarcinoma

V. Graziano, A. Dannhorn, H. Hulme, K. Williamson, H. Buckley, S. A. Karim, S. Y. Lee, B. P. Kaistha, S. Islam, J. E. D. Thaventhiran, F. M. Richards, R. Goodwin, R. Brais, J. P. Morton, S. J. Dovedi, , D. I. Jodrell

This study shows that extracellular adenosine promotes an immunosuppressive microenvironment in PDAC by enhancing myeloid cell infiltration and resistance to immunotherapy, and that blocking adenosine pathway components improves therapeutic outcomes.

bioRxiv · May 24, 2022Cancer Biology

Integrating genomics and multi-platform metabolomics enables metabolite QTL detection in breeding-relevant apple germplasm

E. A. Bilbrey, K. Williamson, E. Hatzakis, D. Doud Miller, J. Fresnedo Ramirez, J. L. Cooperstone

The paper develops a high-throughput integration strategy for genomic and multi-platform metabolomics data to detect metabolite QTL in apple germplasm, identifying novel candidate gene-metabolite relationships.

bioRxiv · Feb 18, 2021Plant Biology

Moderate and intensive mechanical loading differentially modulate the phenotype of tendon stem/progenitor cells in vivo

J. Zhang, D. Nie, K. Williamson, A. McDowell, M. Hogan, J. H.-C. Wang

This study shows that moderate treadmill running maintains tendon homeostasis by promoting TSC differentiation into tenocytes, while intensive treadmill running induces tendinopathy by causing TSCs to differentiate into non-tenocyte cells.

bioRxiv · Nov 9, 2020Cell Biology

Active synthesis of type I collagen homotrimer in Dupuytren's fibrosis is unaffected by anti-TNF-α treatment

K. Williamson, K. J. Lee, E. L. Beamish, A. Carter, J. A. Gumbs, G. Cooper, G. Cheung, D. Brown, R. Pettitt, E. J. Comerford, P. D. Clegg, E. G. Canty-Laird

This study investigates type I collagen synthesis in Dupuytrens disease and finds anti-TNF-α treatment does not reduce collagen production or prevent homotrimer formation.

bioRxiv · Jul 13, 2020Cell Biology