BiochemistrybioRxiv
Inhibition of Tau seeding by targeting Tau nucleation core within neurons with a single domain antibody fragment
C. Danis, E. Dupre, O. Zejneli…·I. Landrieu
This study identifies and optimizes a single domain antibody fragment that inhibits Tau aggregation in vitro and in a mouse model of tauopathy.
DOI 10.1016/j.ymthe.2022.01.009