Author

R. Chatrikhi

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Biochemistry· 1

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Research Focus:drug response / drug discovery· 1 Approach:experimental assay· 1

Frequent Co-Authors

A. J. Frontier· 1 shared A. J. MacRae· 1 shared C. F. Feeney· 1 shared C. L. Kielkopf· 1 shared G. Alachouzos· 1 shared J. L. Jenkins· 1 shared M. J. Pulvino· 1 shared M. J. Walter· 1 shared

Activity by Year

2020-2020 · peak 1/yr

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10 top collaborators · 45 mutual co-author links

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1 shared paperBiochemistry

A. J. Frontier

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1 paper

Recent·Most cited

BiochemistrybioRxivSep 28, 2020

A synthetic small molecule stalls pre-mRNA splicing by promoting an early-stage U2AF2-RNA complex

R. Chatrikhi, C. F. Feeney, M. J. Pulvino…·C. L. Kielkopf

The paper identifies a small molecule that inhibits pre-mRNA splicing by stabilizing an early-stage U2AF2-RNA complex, offering a new strategy for targeting spliceosome assembly.

DOI 10.1016/j.chembiol.2021.02.007

experimental assaydrug response / drug discovery

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