Author

R. Deshaies

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 1

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Research Focus:cell signaling & trafficking· 1 Approach:experimental assay· 1 Organism:human· 1 Assay:proteomics· 1

Frequent Co-Authors

E. Blythe· 1 shared K. Olson· 1 shared V. Chau· 1 shared

Activity by Year

2017-2017 · peak 1/yr

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3 top collaborators · 3 mutual co-author links

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1 shared paperBiochemistry

E. Blythe

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1 paper

Recent·Most cited

BiochemistrybioRxivApr 21, 2017

Ubiquitin and ATP-dependent unfoldase activity of P97/VCP·NPLOC4·UFD1L1 is enhanced by a mutation that causes multisystem proteinopathy

E. Blythe, K. Olson, V. Chau, R. Deshaies

The paper demonstrates that wild-type p97 unfolds proteins via NPLOC4-UFD1L, ATP hydrolysis, and ubiquitination, and shows a p97 mutation enhances this activity, potentially contributing to IBMPFD pathogenesis.

DOI 10.1073/pnas.1706205114

humanproteomics

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