Author

R. DeVita

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 2 Organism:human· 2 Assay:protein structure· 2 Research Focus:drug response / drug discovery· 1 Research Focus:protein structure prediction· 1

Frequent Co-Authors

J. Leandro· 2 shared S. Houten· 2 shared S. Khamrui· 2 shared T. Dodatko· 2 shared A. Sabovic· 1 shared C. Secor· 1 shared C. Suebsuwong· 1 shared C. Yu· 1 shared

Activity by Year

2022-2024 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 36 mutual co-author links

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2 shared papersBiochemistry

J. Leandro

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2 papers

Recent·Most cited

Characterization, structure and inhibition of the human succinyl-CoA:glutarate-CoA transferase, a genetic modifier of glutaric aciduria type 1

S. Khamrui, T. Dodatko, R. Wu, J. Leandro, A. Sabovic, S. Violante, J. R. Cross, E. Marsan, K. Kumar, R. DeVita, M. B. Lazarus, S. Houten

The paper characterizes the human SUGCT enzyme, determines its structure, and identifies inhibitors that may lead to new treatments for glutaric aciduria type 1.

bioRxiv · Feb 7, 2024Biochemistry

Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1

J. Leandro, S. Khamrui, C. Suebsuwong, P.-J. Chen, C. Secor, T. Dodatko, C. Yu, R. Sanchez, R. DeVita, S. Houten, M. Lazarus

The paper characterizes the human LOR domain of AASS, presents its crystal structure, and identifies it as a potential drug target for glutaric aciduria type 1.

bioRxiv · May 20, 2022Biochemistry