BiochemistrybioRxiv
Characterization and structure of the human lysine-2-oxoglutarate reductase domain, a novel therapeutic target for treatment of glutaric aciduria type 1
J. Leandro, S. Khamrui, C. Suebsuwong…·M. Lazarus
The paper characterizes the human LOR domain of AASS, presents its crystal structure, and identifies it as a potential drug target for glutaric aciduria type 1.
DOI 10.1098/rsob.220179