Author

R. Fitzgerald

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cancer Biology· 3 Microbiology· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Organism:human· 3 Assay:bulk RNA-seq· 2 Research Focus:drug response / drug discovery· 2 Assay:metagenomics· 2 Organism:non-human primate· 2 Research Focus:cancer & tumor microenvironment· 1 Research Focus:cell type annotation· 1

Frequent Co-Authors

C. J. Smith· 2 shared C. Keating· 2 shared J. Hinchcliffe· 2 shared m. bolton-warberg· 2 shared R. Davies· 2 shared S. J. Davies· 2 shared S. Whelan· 2 shared A. F. Munro· 1 shared

Activity by Year

2018-2021 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 35 mutual co-author links

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2 shared papersMicrobiology

C. J. Smith

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

High-content profiling reveals a unified model of copper ionophore dependent cell death in oesophageal adenocarcinoma

R. E. Hughes, R. J. Elliott, X. Li, A. F. Munro, A. Makda, R. N. Carter, N. M. Morton, K. Fujihara, N. J. Clemons, R. Fitzgerald, J. R. O'Neill, T. Hupp, N. O. Carragher

This study identifies a unified mechanism of copper ionophore-induced cell death in oesophageal adenocarcinoma using high-content profiling and omic analyses.

bioRxiv · Oct 5, 2021 · PreprintCancer Biology

Key Drivers of Ecological Assembly in the Hindgut of Atlantic Cod (Gadus morhua) when Fed with a Macroalgal Supplemented diet - How Robust Is the Gut to Taxonomic Perturbation?

C. Keating, m. bolton-warberg, J. Hinchcliffe, R. Davies, S. Whelan, A. H. L. Wan, R. Fitzgerald, S. J. Davies, C. J. Smith, U. Z. Z. Ijaz

This study examines ecological assembly processes in the gut microbiome of Atlantic cod fed macroalgae-supplemented diets, finding that dispersal limitation drives community structure in some groups while robustness increases over time.

bioRxiv · Aug 24, 2021 · PreprintMicrobiology

Temporal changes in the gut microbiota in farmed Atlantic cod (Gadus morhua) outweigh the response to diet supplementation with macroalgae.

C. Keating, M. Bolton-Warberg, J. Hinchcliffe, R. Davies, S. Whelan, A. H. Wan, R. Fitzgerald, S. J. Davies, U. Z. Ijaz, C. J. Smith

This study supplements Atlantic cod diets with macroalgae and finds no significant impact on gut microbiota from sea lettuce, but notable effects from egg wrack, with temporal changes outweighing dietary effects.

bioRxiv · Aug 10, 2020Microbiology

THE ROLE OF POTASSIUM CHANNELS IN THE PATHOGENESIS OF GASTROINTESTINAL CANCERS AND THERAPEUTIC POTENTIAL

D. Shorthouse, J. L. Zhuang, E. Rahrmann, C. Kosmidou, K. W. Rahrmann, M. W. J. Hall, B. Greenwood, G. Devonshire, R. Gilbertson, R. Fitzgerald, B. A. Hall

The paper identifies KCNQ channel mutations in 30% of gastrointestinal cancers and shows their therapeutic targetability through drug sensitivity and proliferation inhibition.

bioRxiv · Mar 10, 2020 · PreprintCancer Biology

Patient-specific detection of cancer genes reveals recurrently perturbed processes in esophageal adenocarcinoma

T. Mourikis, L. Benedetti, E. Foxall, D. Temelkovski, J. Nulsen, J. Perner, M. Cereda, J. Lagergren, M. Howell, C. Yau, R. Fitzgerald, P. Scaffidi, F. D. Ciccarelli

This study identifies patient-specific cancer genes in esophageal adenocarcinoma using machine learning, revealing recurrent process perturbations that suggest therapeutic targets.

bioRxiv · Oct 17, 2018 · PreprintCancer Biology