FxR-modulates the gut-vascular barrier by regulating the entry sites for bacterial translocation in experimental cirrhosis
M. Sorribas, M. Jakob, B. Yilmaz, H. Li, D. Stutz, Y. Noser, A. De Gottardi, S. Moghadamrad, M. Hassan, A. Albillos, R. Frances, O. Juanola, I. Spadoni, M. Rescigno, R. Wiest
This study shows that FXR agonists reduce bacterial translocation in cirrhosis by stabilizing the gut-vascular barrier and mucus layer.
bioRxiv · Jul 8, 2019Physiology