Author

R. Harkes

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 1 Cell Biology· 1

Signature Assays, Organisms & Methods

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Research Focus:cell signaling & trafficking· 1 Research Focus:cell type annotation· 1 Approach:deep learning· 1 Research Focus:differential expression· 1 Assay:fluorescence / live-cell microscopy· 1 Organism:human· 1 Assay:imaging· 1 Approach:microscopy & imaging analysis· 1

Frequent Co-Authors

B. van den Broek· 1 shared E. Danen· 1 shared H. E. Balcioglu· 1 shared J. Klarenbeek· 1 shared K. Jalink· 1 shared O. Kukk· 1 shared S. Mukherjee· 1 shared T. Schmidt· 1 shared

Activity by Year

2021-2021 · peak 2/yr

Co-Author Collaboration Network

8 top collaborators · 13 mutual co-author links

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1 shared paperCell Biology

B. van den Broek

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2 papers

Recent·Most cited

Substrate rigidity modulates traction forces and stoichiometry of cell matrix adhesions.

H. E. Balcioglu, R. Harkes, E. Danen, T. Schmidt

The paper quantifies how substrate stiffness affects traction forces and molecular composition of cell-matrix adhesions using superresolution microscopy.

bioRxiv · Oct 29, 2021Biophysics

Dynamic FRET-FLIM based screens of signal transduction pathways: a feasibility study

R. Harkes, O. Kukk, S. Mukherjee, J. Klarenbeek, B. van den Broek, K. Jalink

The paper demonstrates a FRET-FLIM platform for analyzing cAMP dynamics in HeLa cells, finding that PDE3A and PDE10A significantly slow cAMP decay.

bioRxiv · May 23, 2021Cell Biology