Poly(2-oxazoline)-based polyplexes as a PEG-free plasmid DNA delivery platform
D. Yamaleyeva, N. Makita, D. Hwang, M. Haney, R. Jordan, A. V. Kabanov
This study develops PEG-free poly(2-oxazoline) copolymers for efficient plasmid DNA delivery to immune cells, finding that DET-based diblock copolymers outperform other structures in macrophage transfection.
bioRxiv · Dec 18, 2022Bioengineering