One mucosal administration of a live attenuated recombinant COVID-19 vaccine protects non-human primates from SARS-CoV-2
M. F. Tioni, R. Jordan, A. Silva Pena, A. Garg, D. Wu, S. I. Phan, X. Cheng, J. Greenhouse, T. Orekov, D. Valentin, S. Kar, L. Pessaint, H. Andersen, C. C. Stobart, M. H. Bloodworth, , R. S. Tang
This study shows that a single mucosal dose of the live attenuated RSV-based vaccine MV-014-212 protects non-human primates from SARS-CoV-2 infection by reducing viral shedding and inducing neutralizing antibodies.
bioRxiv · Jul 16, 2021Immunology