ImmunologybioRxivPreprint
IL-6 blockade suppresses the blood-brain barrier disorder, leading to prevention of onset of NMOSD
Y. Takeshita, S. Fujikawa, K. Serizawa…·T. Kanda
The paper shows that IL-6 blockade with satralizumab prevents BBB disruption and lymphocyte migration induced by NMO-IgG in EAE and in vitro BBB models.
DOI 10.1101/2021.01.28.428564