Author

T. Kanda

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Immunology· 2 Microbiology· 2 Bioengineering· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 4 Organism:human· 4 Research Focus:cell type annotation· 2 Research Focus:chromatin & epigenetic regulation· 2 Research Focus:cell signaling & trafficking· 1 Assay:ChIP-seq· 1 Research Focus:differential expression· 1 Assay:DNA methylation· 1

Frequent Co-Authors

F. Shimizu· 2 shared Y. Sano· 2 shared B. Obermeier· 1 shared D. Höper· 1 shared D. Motooka· 1 shared D. Rubbenstroth· 1 shared E. E. Nakayama· 1 shared E. Ishikawa· 1 shared

Activity by Year

2020-2024 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersImmunology

F. Shimizu

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

The absence of superinfection exclusion of Borna disease virus 2 maintains genomic polymorphisms in persistently infected cells

T. Kanda, P. D. Santos, D. Höper, M. Beer, D. Rubbenstroth, K. Tomonaga

This study identifies genetic variations in BoDV-2 that enhance its growth and reveals its ability to maintain genomic polymorphisms in infected cells by lacking superinfection exclusion.

bioRxiv · Apr 15, 2024 · PreprintMicrobiology

Identification, crystallization and epitope determination of public TCR shared and expanded in COVID-19 patients

X. Lu, Y. Hosono, S. Ishizuka, M. Nagae, E. Ishikawa, D. Motooka, Y. Ozaki, N. Sax, R. Shinnakasu, T. Inoue, T. Onodera, T. Matsumura, M. Shinkai, T. Sato, S. Nakamura, , S. Yamasaki

The paper identifies and crystallizes public TCRs from SARS-CoV-2-specific Tfh cells in COVID-19 patients, showing they recognize conserved spike epitopes and cross-react with symbiotic bacteria.

bioRxiv · Mar 23, 2021Immunology

IL-6 blockade suppresses the blood-brain barrier disorder, leading to prevention of onset of NMOSD

Y. Takeshita, S. Fujikawa, K. Serizawa, M. Fujisawa, K. Matsuo, J. Nemoto, F. Shimizu, Y. Sano, H. Tomizawa-Shinohara, S. Miyake, R. M. Ransohoff, T. Kanda

The paper shows that IL-6 blockade with satralizumab prevents BBB disruption and lymphocyte migration induced by NMO-IgG in EAE and in vitro BBB models.

bioRxiv · Jan 28, 2021 · PreprintImmunology

CTCF-mediated Genomic Effects of BART Region on Epstein-Barr Virus Chromatin 3D Structure in Gastric Carcinoma Cells

K.-D. Kim, S. Cho, T. Kim, S. Huh, L. Kim, H. Tanizawa, J.-H. Shin, T. Kanda, K. J. Won, P. M. Lieberman, H. Cho, H. Kang

This study investigates how CTCF binding at the BARTp site regulates EBV 3D genome structure and gene expression in EBVaGC cells, showing its role in DNA looping and viral infectivity.

bioRxiv · Dec 3, 2020 · PreprintMicrobiology

An in-vitro BBB-on-a-chip open model of human blood-brain barrier enabling advanced optical imaging

M. Salman, G. Marsh, I. Kusters, M. Delince, G. Di Caprio, S. Upadhyayula, G. De Nola, R. Hunt, K. G. Ohashi, F. Shimizu, Y. Sano, T. Kanda, B. Obermeier, T. Kirchhausen

The paper describes an in-vitro BBB-on-a-chip model that enables high-resolution imaging of blood-brain barrier dynamics.

bioRxiv · Jun 30, 2020 · PreprintBioengineering