ImmunologybioRxivPreprint
Metabolic plasticity of T-cell therapies: multi-omic profiling of interacting human tumor-infiltrating lymphocytes and autologous tumor adoptive cell therapy
M. Martinez-Paniagua, C. Haymaker, J. Robinson…·N. Varadarajan
This study profiles the metabolic interactions between TILs and autologous tumor cells in ACT, finding that responder TILs are more efficient at fatty acid oxidation under starvation.
DOI 10.1101/2022.09.28.509590