Author

R. P. Davis

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Cell Biology· 4

Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 4 Approach:experimental assay· 4 Organism:human· 4 Assay:bulk RNA-seq· 2 Research Focus:differential expression· 2 Research Focus:cell signaling & trafficking· 1 Research Focus:cell-cell communication· 1 Assay:CRISPR screen· 1

Frequent Co-Authors

C. L. Mummery· 4 shared K. O. Brandao· 4 shared C. Grandela· 3 shared M. P. H. Mol· 3 shared A. O. Verkerk· 2 shared B. J. van Meer· 2 shared L. van den Brink· 2 shared L. Yiangou· 2 shared

Activity by Year

2019-2023 · peak 1/yr

Co-Author Collaboration Network

10 top collaborators · 38 mutual co-author links

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4 shared papersCell Biology

C. L. Mummery

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4 papers

Recent·Most cited

Cell BiologybioRxivPreprintDec 11, 2023

Gain of chromosome region 1q31.3 in human iPSCs confers growth advantage and alters contraction in derivative cardiomyocytes

K. O. Brandao, V. Meraviglia, D. Salvatori…·R. P. Davis

The paper shows that a gain of chromosome 1q31.3 in human iPSCs leads to increased TNNT2 expression and altered contraction in derived cardiomyocytes.

DOI 10.1101/2023.12.11.571144

humanbulk RNA-seq

𝕏 PostBluesky

Cell BiologybioRxivDec 8, 2021

STRAIGHT-IN: A platform for high-throughput targeting of large DNA payloads into human pluripotent stem cells

C. Grandela, A. Blanch-Asensio, K. O. Brandao…·R. P. Davis

STRAIGHT-IN enables high-throughput insertion of large DNA payloads into hiPSCs by combining recombinases and CRISPR/Cas9 for precise genomic editing.

DOI 10.1016/j.crmeth.2022.100300

humanCRISPR screen

𝕏 PostBluesky

Cell BiologyStem Cell ReportsPeer-reviewedNov 1, 2020

Isogenic sets of hiPSC-CMs harboring KCNH2 mutations capture location-related phenotypic differences

K. O. Brandao, L. van den Brink, D. C. Miller…·R. P. Davis

The paper uses hiPSC-CMs with KCNH2 mutations to show phenotypic differences based on mutation location, supporting their use in risk stratification for LQT2.

DOI 10.1016/j.stemcr.2020.10.005

humanelectrophysiology

𝕏 PostBluesky

Cell BiologybioRxivJul 14, 2019

Cryopreservation of human pluripotent stem cell-derived cardiomyocytes is not detrimental to their molecular and functional properties

L. van den Brink, K. O. Brandao, C. Grandela…·R. P. Davis

This study shows cryopreservation does not harm the molecular and functional properties of hiPSC-CMs, though it may enrich ventricular myocytes.

DOI 10.1016/j.scr.2019.101698

humanbulk RNA-seq

𝕏 PostBluesky