Male sex and age biases viral burden, viral shedding, and type 1 and 2 interferon responses during SARS-CoV-2 infection in ferrets
M. Francis, B. Richardson, M. McNeil, M. Rioux, M. Foley, A. Ge, R. Pechous, J. Kindrachuk, C. Cameron, C. Richardson, J. Lew, M. Cameron, V. Gerdts, D. Falzarano, A. A. A. Kelvin
This study shows that male sex and age in ferrets affect viral burden, shedding, and interferon responses during SARS-CoV-2 infection, with older males showing delayed antiviral responses.
bioRxiv · Jan 12, 2021Microbiology