Author

R. Planque

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biophysics· 2 Ecology· 1 Evolutionary Biology· 1

Signature Assays, Organisms & Methods

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Approach:statistical model· 3 Approach:biophysical modeling· 1 Assay:electrophysiology· 1 Research Focus:host-pathogen & immune response· 1 Organism:mouse· 1 Research Focus:synaptic & neural circuits· 1

Frequent Co-Authors

F. J. Bruggeman· 2 shared A. Bueno-Orovio· 1 shared A. Galione· 1 shared A. J. Tjalma· 1 shared D. H. de Groot· 1 shared E. Bosch· 1 shared J. Schouten· 1 shared O. Diekmann· 1 shared

Activity by Year

2019-2022 · peak 2/yr

Co-Author Collaboration Network

10 top collaborators · 14 mutual co-author links

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2 shared papersEvolutionary Biology

F. J. Bruggeman

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Author profile →

4 papers

Recent·Most cited

Lysosomal calcium loading promotes arrhythmias by potentiating ryanodine receptor release

Z. Meng, R.-A. Capel, S. J. Bose, E. Bosch, S. d. Jong, R. Planque, A. Galione, R. A. Burton, A. Bueno-Orovio

This study shows lysosomal calcium handling promotes RyR spontaneous release by increasing SR-junction calcium gradient, and blocking lysosomal function reduces arrhythmias.

bioRxiv · Nov 9, 2022 · PreprintBiophysics

Poor sensing maximises microbial fitness when few out of many signals are sensed

A. J. Tjalma, R. Planque, F. J. Bruggeman

The paper develops an evolutionary model showing that low-fidelity sensing can maximize microbial fitness when only a few signals are sensed among many possible ones.

bioRxiv · Apr 9, 2020 · PreprintEvolutionary Biology

Cell fate determination by Lamarckian molecule-inheritance and chance

F. J. Bruggeman, J. Schouten, D. H. de Groot, R. Planque

The paper develops a theory to explain cellular heterogeneity by considering stochastic ancestral events in isogenic cell populations, showing that copy-number noise is unavoidable due to cell division stochasticity.

bioRxiv · Apr 24, 2019 · PreprintBiophysics

The winner takes it all: how semelparous insects can become periodical

O. Diekmann, R. Planque

The paper explains the periodic emergence of Magicicada species through density-dependent competition and predation, showing how most year classes go extinct except one.

bioRxiv · Feb 5, 2019Ecology