Cell BiologybioRxiv
Human adipose-derived mesenchymal stromal cells from face and abdomen undergo replicative senescence and loss of genetic integrity after long-term culture
P. B. Delben, H. D. Zomer, C. A. Silva…·A. G. Trentin
This study shows that human facial and abdominal adipose-derived mesenchymal stromal cells undergo replicative senescence and genetic instability after long-term culture, with facial cells showing fewer mitotic errors.
DOI 10.1016/j.yexcr.2021.112740