BioengineeringbioRxiv
Combination of NY-ESO-1-TCR-T-cells coengineered to secrete SiRPalpha decoys with anti-tumor antibodies to augment macrophage phagocytosis
E. Stefanidis, A. Semilietof, J. Pujol…·M. Irving
This study combines NY-ESO-1 TCR-T cells secreting SiRPalpha decoys with anti-tumor antibodies to enhance macrophage phagocytosis and improve tumor control.
DOI 10.1172/jci161660