Author

R. Stehle

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Biology Disciplines

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Biochemistry· 3 Biophysics· 2

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Research Focus:cell signaling & trafficking· 2 Research Focus:protein folding & dynamics· 2 Assay:proteomics· 2 Approach:statistical model· 2 Assay:structural biology· 2 Research Focus:cell type annotation· 1 Research Focus:chromatin & epigenetic regulation· 1

Frequent Co-Authors

M. Sattler· 4 shared A. Geerlof· 3 shared A. A. Kawale· 1 shared A. Bach· 1 shared A. C. Messias· 1 shared A. Jussupow· 1 shared A. Wulf· 1 shared B. Simon· 1 shared

Activity by Year

2020-2022 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 23 mutual co-author links

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4 shared papersBiochemistry

M. Sattler

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Author profile →

5 papers

Recent·Most cited

Structural basis for specific RNA recognition by the alternative splicing factor RBM5

K. Soni, P. Jagtap, S. Martinez-Lumbreras, S. Bonnal, A. Geerlof, R. Stehle, B. Simon, J. Valcarcel, M. Sattler

This paper investigates how RBM5's RNA-binding domains recognize specific RNA motifs to regulate alternative splicing, revealing structural and cooperative mechanisms.

bioRxiv · Dec 12, 2022Biochemistry

Npl3 functions in mRNP assembly by recruitment of mRNP components to the transcription site and their transfer onto the mRNA

P. Keil, A. Wulf, N. Kachariya, S. Reuscher, K. Huehn, I. Silbern, J. Altmueller, R. Stehle, K. Zarnack, M. Sattler, H. Urlaub, K. Straesser

The paper identifies Npl3's role in mRNP assembly by recruiting components to the transcription site and transferring them onto mRNA.

bioRxiv · Jul 22, 2022Biochemistry

Phosphate binding induced force-reversal occurs via slow backward cycling of cross-bridges

R. Stehle

The paper shows that increasing phosphate concentration reciprocally affects force and the rate constant of force redevelopment in cardiac myofibrils, indicating slow backward cycling of cross-bridges due to Pi binding or force-reversal.

bioRxiv · Aug 20, 2020 · PreprintBiophysics

Structural evolution of the tissue-specific U2AF2 paralog and alternative splicing factor LS2

A. A. Kawale, J. M. Taliaferro, H.-S. Kang, C. Hartmueller, A. Geerlof, R. Stehle, C. Burge, D. C. Rio, M. Sattler

The paper determines the structure of the Drosophila LS2 protein's RRM domains and shows they interact with G quadruplex RNA motifs to regulate alternative splicing.

bioRxiv · Aug 15, 2020 · PreprintBiochemistry

Molecular recognition and dynamics of linear poly-ubiquitins: integrating coarse-grain simulations and experiments

A. Jussupow, A. C. Messias, R. Stehle, A. Geerlof, S. M. O. Solbak, A. Bach, M. Sattler, C. Camilloni

This paper combines coarse-grain simulations and experiments to study the conformational dynamics of linear poly-ubiquitin chains and their interaction with NEMO.

bioRxiv · Apr 14, 2020 · PreprintBiophysics