A recombinant fragment of Human surfactant protein D binds Spike protein and inhibits infectivity and replication of SARS-CoV-2 in clinical samples
T. Madan, B. Biswas, P. Varghese, R. Subedi, H. Pandit, S. Idicula-Thomas, I. Kundu, S. B. Rooge, R. Aggarwal, D. Tripathi, S. Kaur, E. Gupta, S. Gupta, U. Kishore
This study shows that a recombinant fragment of human SP-D inhibits SARS-CoV-2 spike protein binding to ACE-2 and reduces viral replication in clinical samples.
bioRxiv · Dec 18, 2020Immunology