MicrobiologybioRxiv
Characterizing a thermostable Cas9 for bacterial genome editing and silencing
I. Mougiakos, P. Mohanraju, E. F. Bosma…·J. van der Oost
This study identifies and characterizes ThermoCas9, a thermostable Cas9 variant active across a broad temperature range, and develops tools for bacterial genome editing and silencing at elevated temperatures.
DOI 10.1038/s41467-017-01591-4