Aerobic exercise promotes PDAC vascular normalization through S1PR1 signaling in tumor endothelial cells
R. Ballaro, S. Pareek, J. Lee, H. Patel, P. Tirumala, G. Liu, K. Hayek, H. Savage, B. Guerrouahen, A. Ngo-Huang, N. Parker, M. H. Katz, M. Petzel, F. McAllister, R. Wright, , K. Schadler
This study shows aerobic exercise improves PDAC vascular function and chemotherapy efficacy via S1PR1 signaling in tumor endothelial cells.
bioRxiv · Feb 14, 2024 · PreprintCancer Biology