PhysiologyiSciencePeer-reviewed
Partially differentiated enterocytes in ileal and distal-colonic human F508del-CF-enteroids 1 secrete fluid in response to forskolin and linaclotide.
Rong Yan, Zixin Zhang, Hugo R. de Jonge…·Varsha Singh
The paper shows partially differentiated CFTR-mutant enteroids secrete fluid in response to forskolin and linaclotide, with reduced efficacy compared to healthy enteroids.
3 citations