Author

Ran Cheng

Stanford Medicine

Listed by name: these papers carry no ORCID for this author, so different people with the same name may be mixed together.

Same name, identified by ORCID

Biology Disciplines

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Cancer Biology· 2 Bioengineering· 1 Molecular Biology· 1

Signature Assays, Organisms & Methods

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Approach:experimental assay· 3 Assay:proteomics· 3 Research Focus:cell type annotation· 2 Research Focus:differential expression· 2 Organism:human· 2 Organism:mouse· 2 Approach:statistical model· 2 Assay:bulk RNA-seq· 1

Frequent Co-Authors

János DemeteriD· 2 shared Michael Cory BassikiD· 2 shared Peter K. JacksoniD· 2 shared Aicha R. Mabene· 1 shared Akhilesh PandeyiD· 1 shared Alexandros P. DrainasiD· 1 shared Andrew M. LareyiD· 1 shared Anthony M. Boutelle· 1 shared

Activity by Year

2020-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 19 mutual co-author links

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2 shared papersCancer Biology

János DemeterORCID

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Author profile →

4 papers

Recent·Most cited

Proteomic Analysis of PTEN-Deficient Cells Reveals Src-Mediated Upregulation of EphA2 and Therapeutic Potential of Dual Inhibition

Qiong Wang, Xiangyi Kong, Hongming Song, Li Wang, Lingrui Li, Xiaonan Hou, Santosh Renuse, Muhammad Saddiq Zahari, Ran Cheng, Mahmood Khan, Jidong Wang, Kiran Kumar Mangalaparthi, Lin Fang, Tamara Levin Lotan, Ben Ho Park, , Xinyan Wu

This study identifies Src-mediated upregulation of EphA2 in PTEN-deficient cells and shows that combined AKT and Src inhibition synergistically suppresses tumor growth.

Molecular & Cellular Proteomics · Oct 22, 2025Peer-reviewedCancer Biology

Orthogonal and Robust Analytics Enable Reproducible and Scalable Manufacturing of High Purity Extracellular Vesicles Derived from Mesenchymal Stromal Cells

Mehdi Dehghani, Meng Chai, Nazanin Talebloo, Molly Morrissey, Andrew M. Larey, Yuriy Kim, Camille V. Trinidad, Deepika Joshi, Yuxuan Wu, Yichen Zhong, Ran Cheng, Yisheng Lu, Behnaz Lahooti, Mohammad Naimul Islam, Zheng Zhao, , Ethan Kishimori

This paper develops an analytical toolbox and scalable downstream processing workflow for high purity extracellular vesicles from mesenchymal stromal cells, using orthogonal methods to improve reproducibility and purity.

bioRxiv · Aug 26, 2025 · PreprintBioengineering

Integrative multiomic approaches reveal ZMAT3 and p21 as conserved hubs in the p53 tumor suppression network

Anthony M. Boutelle, Aicha R. Mabene, David Yao, Haiqing Xu, Mengxiong Wang, Yuning J. Tang, Steven S. Lopez, Sauradeep Sinha, János Demeter, Ran Cheng, Brooks A. Benard, Edel M. McCrea, Liz J. Valente, Alexandros P. Drainas, Martin Fischer, , Laura Donatella Attardi

The paper identifies ZMAT3 and CDKN1A as key hubs in the p53 tumor suppression network through integrative multiomic analyses in a mouse model.

Cell Death and Differentiation · Apr 22, 2025Peer-reviewedCancer Biology

A CRISPR-based genome-wide screen for adipogenesis reveals new insights into mitotic expansion and lipogenesis.

Rachel E. Turn, Keren I. Hilgendorf, Carl T. Johnson, Kyuho Han, Atefeh Rabiee, János Demeter, Mohammad Ovais Aziz‐Zanjani, Pablo Domizi, Ran Cheng, Yingdi Zhu, Zewen Jiang, Katrin J. Svensson, Michael Cory Bassik, Peter K. Jackson

The paper uses a CRISPR-based screen in 3T3-L1 cells to identify regulators of adipogenesis, finding that protein translation and stability mechanisms are critical for adipocyte expansion and lipogenesis.

bioRxiv · Jul 13, 2020 · PreprintMolecular Biology