Author

Andrew M. Larey

University of GeorgiaORCID 0000-0001-6460-643XUnclaimed ORCID profile · follow to get notified of new preprints

Biology Disciplines

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Signature Assays, Organisms & Methods

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Research Focus:cell type annotation· 5 Approach:experimental assay· 4 Organism:human· 3 Assay:proteomics· 3 Research Focus:clustering· 2 Research Focus:differential expression· 1 Assay:metabolomics· 1 Approach:statistical model· 1

Frequent Co-Authors

Kanupriya R. Daga· 4 shared Ross A. MarkleiniD· 4 shared Hannah M. HyndsiD· 2 shared Jana M. CarpenteriD· 2 shared Kelly Marie HinesiD· 2 shared Maria G. Morfin· 2 shared Thomas M. Spoerer· 2 shared Behnaz LahootiiD· 1 shared

Activity by Year

2024-2025 · peak 3/yr

Co-Author Collaboration Network

10 top collaborators · 24 mutual co-author links

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Curved chords = mutual co-authorship

4 shared papersBioengineering

Kanupriya R. Daga

Mutual co-authors in cluster

Author profile →

5 papers

Recent·Most cited

BioengineeringbioRxivPreprintAug 26, 2025

Orthogonal and Robust Analytics Enable Reproducible and Scalable Manufacturing of High Purity Extracellular Vesicles Derived from Mesenchymal Stromal Cells

Mehdi Dehghani, Meng Chai, Nazanin Talebloo…·Ethan Kishimori

This paper develops an analytical toolbox and scalable downstream processing workflow for high purity extracellular vesicles from mesenchymal stromal cells, using orthogonal methods to improve reproducibility and purity.

DOI 10.1101/2025.08.26.672476

humanproteomics

𝕏 PostBluesky

BioengineeringStem Cell Reviews and ReportsPeer-reviewedAug 12, 2025

Development of a High-throughput Morphological Assay for Evaluating Mesenchymal Stromal Cell-derived Extracellular Vesicle Modulation of Brain Pericyte Secretory Phenotype

Courtney E. Campagna, Andrew M. Larey, Kanupriya R. Daga…·Ross A. Marklein

This study develops a high-throughput morphological assay to evaluate how MSC-EVs modulate brain pericyte secretory phenotype, showing distinct morphological responses under different manufacturing conditions.

3 citations

experimental assaycell type annotation

𝕏 PostBluesky

BioengineeringStem Cell Research & TherapyPeer-reviewedMar 7, 2025

High Throughput Morphological Screening Identifies Chemically Defined Media for Mesenchymal Stromal Cells that Enhances Proliferation and Supports Maintenance of Immunomodulatory Function

Thomas M. Spoerer, Andrew M. Larey, Winifred Asigri…·Ross A. Marklein

5 citations

experimental assaycell type annotation

𝕏 PostBluesky

BioengineeringJournal of Biological EngineeringPeer-reviewedOct 17, 2024

Microglia Morphological Response to Mesenchymal Stromal Cell Extracellular Vesicles Demonstrates EV Therapeutic Potential for Modulating Neuroinflammation

Kanupriya R. Daga, Andrew M. Larey, Maria G. Morfin…·Ross A. Marklein

This paper demonstrates that MSC-EVs modulate microglia morphology and cytokine secretion, suggesting their therapeutic potential for neuroinflammation, and introduces a high-throughput morphological screening method for EV bioactivity.

14 citations

humanproteomics

𝕏 PostBluesky

BioengineeringBioactive MaterialsPeer-reviewedMar 20, 2024

High throughput screening of mesenchymal stromal cell morphological response to inflammatory signals for bioreactor-based manufacturing of extracellular vesicles that modulate microglia

Andrew M. Larey, Thomas M. Spoerer, Kanupriya R. Daga…·Ross A. Marklein

The paper screens MSC morphology in response to inflammatory priming to identify optimal conditions for EV production and microglia modulation in bioreactors.

19 citations

humanproteomics

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