Author

Rebecca Scott

Newcastle University

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Biophysics· 1

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Approach:experimental assay· 1 Organism:human· 1 Research Focus:protein folding & dynamics· 1 Assay:proteomics· 1

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Anita Wittner· 1 shared Claire JenningsiD· 1 shared Eleanor K. Wright· 1 shared Gina M. DoodyiD· 1 shared Ian HicksoniD· 1 shared Julie A. TuckeriD· 1 shared Lan-Zhen Wang· 1 shared Martin E. M. NobleiD· 1 shared

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2025-2025 · peak 1/yr

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1 shared paperBiophysics

Anita Wittner

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1 paper

Recent·Most cited

BiophysicsbioRxivPreprintMar 12, 2025

Structural, biophysical and biological analysis and characterisation of IRF4 DNA-binding domain mutations associated with multiple myeloma

Natalie J. Tatum, Rebecca Scott, Gina M. Doody…·Martin E. M. Noble

The paper analyzes IRF4 DNA-binding domain mutations in multiple myeloma, finding they affect DNA-binding kinetics and thermal stability but not affinity, and may confer improved prognosis.

DOI 10.1101/2025.03.12.642038

humanproteomics

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